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A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

Disrupted regulation of cellular processes is considered one of the hallmarks of cancer. We analyze metabolomic and transcriptomic profiles jointly collected from breast cancer and hepatocellular carcinoma patients to explore the associations between the expression of metabolic enzymes and the level...

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Detalles Bibliográficos
Autores principales: Auslander, Noam, Yizhak, Keren, Weinstock, Adam, Budhu, Anuradha, Tang, Wei, Wang, Xin Wei, Ambs, Stefan, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942812/
https://www.ncbi.nlm.nih.gov/pubmed/27406679
http://dx.doi.org/10.1038/srep29662