Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer’s disease

Neprilysin (NEP) is the most important Aβ-degrading enzyme. Its expression level decreases with age and inversely correlated with amyloid accumulation, suggesting its correlation with the late-onset of Alzheimer’s disease. Recently, many reports showed that upregulating NEP level is a promising stra...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Po-Ting, Chen, Zih-ten, Hou, Wen-Chi, Yu, Lung-Chih, Chen, Rita P.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942833/
https://www.ncbi.nlm.nih.gov/pubmed/27407064
http://dx.doi.org/10.1038/srep29760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942833/
https://www.ncbi.nlm.nih.gov/pubmed/27407064
http://dx.doi.org/10.1038/srep29760

Ejemplares similares