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Archaeoglobus Fulgidus DNA Polymerase D: A Zinc-Binding Protein Inhibited by Hypoxanthine and Uracil

Archaeal family-D DNA polymerases (Pol-D) comprise a small (DP1) proofreading subunit and a large (DP2) polymerase subunit. Pol-D is one of the least studied polymerase families, and this publication investigates the enzyme from Archaeoglobus fulgidus (Afu Pol-D). The C-terminal region of DP2 contai...

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Detalles Bibliográficos
Autores principales: Abellón-Ruiz, Javier, Waldron, Kevin J., Connolly, Bernard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942837/
https://www.ncbi.nlm.nih.gov/pubmed/27320386
http://dx.doi.org/10.1016/j.jmb.2016.06.008