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Novel cell-based in vitro screen to identify small-molecule inhibitors against intracellular replication of Cryptococcus neoformans in macrophages

The fungal pathogen Cryptococcus neoformans poses a major threat to immunocompromised patients and is a leading killer of human immunodeficiency virus (HIV)-infected patients worldwide. Cryptococci are known to manipulate host macrophages and can either remain latent or proliferate intracellularly w...

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Detalles Bibliográficos
Autores principales: Samantaray, Sweta, Correia, Joao N., Garelnabi, Mariam, Voelz, Kerstin, May, Robin C., Hall, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942879/
https://www.ncbi.nlm.nih.gov/pubmed/27289450
http://dx.doi.org/10.1016/j.ijantimicag.2016.04.018