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Novel cell-based in vitro screen to identify small-molecule inhibitors against intracellular replication of Cryptococcus neoformans in macrophages
The fungal pathogen Cryptococcus neoformans poses a major threat to immunocompromised patients and is a leading killer of human immunodeficiency virus (HIV)-infected patients worldwide. Cryptococci are known to manipulate host macrophages and can either remain latent or proliferate intracellularly w...
Autores principales: | Samantaray, Sweta, Correia, Joao N., Garelnabi, Mariam, Voelz, Kerstin, May, Robin C., Hall, Rebecca A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942879/ https://www.ncbi.nlm.nih.gov/pubmed/27289450 http://dx.doi.org/10.1016/j.ijantimicag.2016.04.018 |
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