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Development of a two-step protocol for culture expansion of human annulus fibrosus cells with TGF-β1 and FGF-2

BACKGROUND: Different biologic approaches to treat disc regeneration, including growth factors (GFs) application, are currently under investigation. Human annulus fibrosus (hAF) repair or regeneration is one of the key elements for maintenance and restoration of nucleus pulposus function. However, s...

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Detalles Bibliográficos
Autores principales: Chou, Po-Hsin, Wang, Shih-Tien, Ma, Hsiao-Li, Liu, Chien-Lin, Chang, Ming-Chau, Lee, Oscar Kuang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942939/
https://www.ncbi.nlm.nih.gov/pubmed/27405858
http://dx.doi.org/10.1186/s13287-016-0332-1