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Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors
Evidence indicates that autoimmunity can be triggered by virus-specific CD8(+) T cells that crossreact with self-derived peptide epitopes presented on the cell surface by major histocompatibility complex class I (MHCI) molecules. Identification of the associated viral pathogens is challenging becaus...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943067/ https://www.ncbi.nlm.nih.gov/pubmed/26846725 http://dx.doi.org/10.1038/icb.2016.12 |