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Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data
Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sites, resulting...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943204/ https://www.ncbi.nlm.nih.gov/pubmed/27324920 http://dx.doi.org/10.1093/gbe/evw137 |