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Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data

Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sites, resulting...

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Detalles Bibliográficos
Autores principales: Kainov, Yaroslav A., Aushev, Vasily N., Naumenko, Sergey A., Tchevkina, Elena M., Bazykin, Georgii A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943204/
https://www.ncbi.nlm.nih.gov/pubmed/27324920
http://dx.doi.org/10.1093/gbe/evw137