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Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial‐to‐Mesenchymal Transition

BACKGROUND: The adult mammalian heart responds to cardiac injury by formation of persistent fibrotic scar that eventually leads to heart failure. In contrast, the neonatal mammalian heart reacts to injury by the development of transient fibrotic tissue that is eventually replaced by regenerated card...

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Detalles Bibliográficos
Autores principales: Mizutani, Makiko, Wu, Joseph C., Nusse, Roeland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943236/
https://www.ncbi.nlm.nih.gov/pubmed/27068625
http://dx.doi.org/10.1161/JAHA.115.002457