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5‐Lipoxygenase Gene Variants Are Not Associated With Atherosclerosis or Incident Coronary Heart Disease in the Multi‐Ethnic Study of Atherosclerosis Cohort

BACKGROUND: The arachidonate 5‐lipoxygenase enzyme plays a crucial role in mediating inflammation to maintain homeostasis, yet certain allelic variants of the 5‐lipoxygenase gene, ALOX5, may increase risk of atherosclerosis and coronary heart disease (CHD). Further, relations between ALOX5 and disea...

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Detalles Bibliográficos
Autores principales: Tsai, Michael Y., Cao, Jing, Steffen, Brian T., Weir, Natalie L., Rich, Stephen S., Liang, Shuang, Guan, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943258/
https://www.ncbi.nlm.nih.gov/pubmed/27025886
http://dx.doi.org/10.1161/JAHA.115.002814