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High quality, small molecule-activity datasets for kinase research

Kinases regulate cell growth, movement, and death. Deregulated kinase activity is a frequent cause of disease. The therapeutic potential of kinase inhibitors has led to large amounts of published structure activity relationship (SAR) data. Bioactivity databases such as the Kinase Knowledgebase (KKB)...

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Detalles Bibliográficos
Autores principales: Sharma, Rajan, Schürer, Stephan C., Muskal, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943296/
https://www.ncbi.nlm.nih.gov/pubmed/27429748
http://dx.doi.org/10.12688/f1000research.8950.3