Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold

Tumor models based on cancer cell lines cultured two-dimensionally (2D) on plastic lack histological complexity and functionality compared to the native microenvironment. Xenogenic mouse tumor models display higher complexity but often do not predict human drug responses accurately due to species-sp...

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Detalles Bibliográficos
Autores principales: Nietzer, Sarah, Baur, Florentin, Sieber, Stefan, Hansmann, Jan, Schwarz, Thomas, Stoffer, Carolin, Häfner, Heide, Gasser, Martin, Waaga-Gasser, Ana Maria, Walles, Heike, Dandekar, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943469/
https://www.ncbi.nlm.nih.gov/pubmed/27137941
http://dx.doi.org/10.1089/ten.tec.2015.0557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943469/
https://www.ncbi.nlm.nih.gov/pubmed/27137941
http://dx.doi.org/10.1089/ten.tec.2015.0557

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