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Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein

Numerous broadly neutralizing antibodies (Abs) target epitopes that are formed or enhanced during mature HIV envelope formation (i.e. quaternary epitopes). Generally, it is thought that Env epitopes that induce broadly neutralizing Abs are difficult to access and poorly immunogenic because of the ch...

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Detalles Bibliográficos
Autores principales: Hicar, Mark D., Chen, Xuemin, Sulli, Chidananda, Barnes, Trevor, Goodman, Jason, Sojar, Hakimuddin, Briney, Bryan, Willis, Jordan, Chukwuma, Valentine U., Kalams, Spyros A., Doranz, Benjamin J., Spearman, Paul, Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943599/
https://www.ncbi.nlm.nih.gov/pubmed/27411063
http://dx.doi.org/10.1371/journal.pone.0158861