Cargando…

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

We performed a quantitative analysis of the HLA restriction, antigen and epitope specificity of human pathogen specific responses in healthy individuals infected with M. tuberculosis (Mtb), in a South African cohort as a test case. The results estimate the breadth of T cell responses for the first t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindestam Arlehamn, Cecilia S., McKinney, Denise M., Carpenter, Chelsea, Paul, Sinu, Rozot, Virginie, Makgotlho, Edward, Gregg, Yolande, van Rooyen, Michele, Ernst, Joel D., Hatherill, Mark, Hanekom, Willem A., Peters, Bjoern, Scriba, Thomas J., Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943605/
https://www.ncbi.nlm.nih.gov/pubmed/27409590
http://dx.doi.org/10.1371/journal.ppat.1005760