Structural study of the G57W mutant of human gamma-S-crystallin, associated with congenital cataract

PURPOSE: Human γS-crystallin (CrygS) is an important component of the human eye lens nucleus and cortex. The mutation G57W in the molecule is reported to be associated with congenital cataract in children. We compare the conformational features and aggregation properties of the mutant protein G57W w...

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Detalles Bibliográficos
Autores principales: Khan, Ismail, Chandani, Sushil, Balasubramanian, Dorairajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943855/
https://www.ncbi.nlm.nih.gov/pubmed/27440995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943855/
https://www.ncbi.nlm.nih.gov/pubmed/27440995

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