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GLUT1 activity contributes to the impairment of PEDF secretion by the RPE

PURPOSE: In this study, we aimed to understand whether glucose transporter 1 (GLUT1) activity affects the secretion capacity of antiangiogenic factor pigment epithelium-derived factor (PEDF) by the RPE cells, thus explaining the reduction in PEDF levels observed in patients with diabetic retinopathy...

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Detalles Bibliográficos
Autores principales: Calado, Sofia M., Alves, Liliana S., Simão, Sónia, Silva, Gabriela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943856/
https://www.ncbi.nlm.nih.gov/pubmed/27440994