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Mesenchymal-epithelial signalling in tumour microenvironment: role of high-mobility group Box 1

Glucose deprivation, hypoxia and acidosis are characteristic features of the central core of most solid tumours. Myofibroblasts are stromal cells present in many such solid tumours, including those of the colon, and are known to be involved in all stages of tumour progression. HMGB1 is a nuclear pro...

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Detalles Bibliográficos
Autores principales: Sharma, Sikander, Evans, Andrew, Hemers, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943978/
https://www.ncbi.nlm.nih.gov/pubmed/26979829
http://dx.doi.org/10.1007/s00441-016-2389-7