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Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H(2)S Releasing Donors in Mammalian Cells

H(2)S is an important signalling molecule involved in diverse biological processes. It mediates the formation of cysteine persulfides (R-S-SH), which affect the activity of target proteins. Like thiols, persulfides show reactivity towards electrophiles and behave similarly to other cysteine modifica...

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Detalles Bibliográficos
Autores principales: Longen, Sebastian, Richter, Florian, Köhler, Yvette, Wittig, Ilka, Beck, Karl-Friedrich, Pfeilschifter, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944133/
https://www.ncbi.nlm.nih.gov/pubmed/27411966
http://dx.doi.org/10.1038/srep29808