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Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H(2)S Releasing Donors in Mammalian Cells
H(2)S is an important signalling molecule involved in diverse biological processes. It mediates the formation of cysteine persulfides (R-S-SH), which affect the activity of target proteins. Like thiols, persulfides show reactivity towards electrophiles and behave similarly to other cysteine modifica...
Autores principales: | Longen, Sebastian, Richter, Florian, Köhler, Yvette, Wittig, Ilka, Beck, Karl-Friedrich, Pfeilschifter, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944133/ https://www.ncbi.nlm.nih.gov/pubmed/27411966 http://dx.doi.org/10.1038/srep29808 |
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