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Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway

Annexin A1 (ANXA1) is a Ca(2+)-binding protein over-expressed in pancreatic cancer (PC). We recently reported that extracellular ANXA1 mediates PC cell motility acting on Formyl Peptide Receptors (FPRs). Here, we describe other mechanisms by which intracellular ANXA1 could mediate PC progression. We...

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Detalles Bibliográficos
Autores principales: Belvedere, Raffaella, Bizzarro, Valentina, Forte, Giovanni, Dal Piaz, Fabrizio, Parente, Luca, Petrella, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944142/
https://www.ncbi.nlm.nih.gov/pubmed/27412958
http://dx.doi.org/10.1038/srep29660