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Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway
Annexin A1 (ANXA1) is a Ca(2+)-binding protein over-expressed in pancreatic cancer (PC). We recently reported that extracellular ANXA1 mediates PC cell motility acting on Formyl Peptide Receptors (FPRs). Here, we describe other mechanisms by which intracellular ANXA1 could mediate PC progression. We...
Autores principales: | Belvedere, Raffaella, Bizzarro, Valentina, Forte, Giovanni, Dal Piaz, Fabrizio, Parente, Luca, Petrella, Antonello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944142/ https://www.ncbi.nlm.nih.gov/pubmed/27412958 http://dx.doi.org/10.1038/srep29660 |
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