Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunity

SAMHD1 is a type I interferon (IFN) inducible host innate immunity restriction factor that inhibits an early step of the viral life cycle. The underlying mechanisms of SAMHD1 transcriptional regulation remains elusive. Here, we report that inducing SAMHD1 upregulation is part of an early intrinsic i...

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Detalles Bibliográficos
Autores principales: Yang, Shen, Zhan, Yuan, Zhou, Yanjun, Jiang, Yifeng, Zheng, Xuchen, Yu, Lingxue, Tong, Wu, Gao, Fei, Li, Liwei, Huang, Qinfeng, Ma, Zhiyong, Tong, Guangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944147/
https://www.ncbi.nlm.nih.gov/pubmed/27411355
http://dx.doi.org/10.1038/srep29665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944147/
https://www.ncbi.nlm.nih.gov/pubmed/27411355
http://dx.doi.org/10.1038/srep29665

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