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Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic and mucosal immune responses in BALB/c mice by mucosal administration

The HIV-1 membrane proximal external region (MPER) that is targeted by several broadly neutralizing antibodies (BNAbs) has been considered a potential immunogen for vaccine development. However, to date the immunogenicity of these BNAb epitopes has not been made sufficiently adequate. In the present...

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Detalles Bibliográficos
Autores principales: Li, Qing-Hai, Jin, Gang, Wang, Jia-Ye, Li, Hai-Ning, Liu, Huidi, Chang, Xiao-Yun, Wang, Fu-Xiang, Liu, Shu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944174/
https://www.ncbi.nlm.nih.gov/pubmed/27411313
http://dx.doi.org/10.1038/srep29556