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Anti-allodynic effect of intrathecal processed Aconitum jaluense is associated with the inhibition of microglial activation and P2X7 receptor expression in spinal cord

BACKGROUND: For their analgesic and anti-arthritic effects, Aconitum species have been used in folk medicine in some East Asian countries. Although their analgesic effect is attributed to its action on voltage-dependent sodium channels, they also suppress purinergic receptor expression in dorsal roo...

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Detalles Bibliográficos
Autores principales: Yang, Jihoon, Park, Keun Suk, Yoon, Jae Joon, Bae, Hong-Beom, Yoon, Myung Ha, Choi, Jeong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944236/
https://www.ncbi.nlm.nih.gov/pubmed/27411500
http://dx.doi.org/10.1186/s12906-016-1201-2