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Modeling and simulation of maintenance treatment in first-line non-small cell lung cancer with external validation

BACKGROUND: Maintenance treatment (MTx) in responders following first-line treatment has been investigated and practiced for many cancers. Modeling and simulation may support interpretation of interim data and development decisions. We aimed to develop a modeling framework to simulate overall surviv...

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Detalles Bibliográficos
Autores principales: Han, Kelong, Claret, Laurent, Sandler, Alan, Das, Asha, Jin, Jin, Bruno, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944249/
https://www.ncbi.nlm.nih.gov/pubmed/27412292
http://dx.doi.org/10.1186/s12885-016-2455-2