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Insights into APC/C: from cellular function to diseases and therapeutics

Anaphase-promoting complex/cyclosome (APC/C) is a multifunctional ubiquitin-protein ligase that targets different substrates for ubiquitylation and therefore regulates a variety of cellular processes such as cell division, differentiation, genome stability, energy metabolism, cell death, autophagy a...

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Detalles Bibliográficos
Autores principales: Zhou, Zhuan, He, Mingjing, Shah, Anil A., Wan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944252/
https://www.ncbi.nlm.nih.gov/pubmed/27418942
http://dx.doi.org/10.1186/s13008-016-0021-6