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Enhanced IgG4 production by follicular helper 2 T cells and the involvement of follicular helper 1 T cells in the pathogenesis of IgG4-related disease

BACKGROUND: The aim of this study was to elucidate the function of circulating follicular helper T (Tfh) cell subsets in helping B cells in patients with active, untreated IgG4-related disease (IgG4-RD) and determine their relationship with disease activity. METHODS: Seventeen consecutive patients w...

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Detalles Bibliográficos
Autores principales: Akiyama, Mitsuhiro, Yasuoka, Hidekata, Yamaoka, Kunihiro, Suzuki, Katsuya, Kaneko, Yuko, Kondo, Harumi, Kassai, Yoshiaki, Koga, Keiko, Miyazaki, Takahiro, Morita, Rimpei, Yoshimura, Akihiko, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944254/
https://www.ncbi.nlm.nih.gov/pubmed/27411315
http://dx.doi.org/10.1186/s13075-016-1064-4