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Platelet lysate as a substitute for animal serum for the ex-vivo expansion of mesenchymal stem/stromal cells: present and future

The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the transplanted host. Additionally, FBS production came under scrutiny due to animal welfare concerns. Platelet derivatives have...

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Detalles Bibliográficos
Autores principales: Astori, Giuseppe, Amati, Eliana, Bambi, Franco, Bernardi, Martina, Chieregato, Katia, Schäfer, Richard, Sella, Sabrina, Rodeghiero, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944312/
https://www.ncbi.nlm.nih.gov/pubmed/27411942
http://dx.doi.org/10.1186/s13287-016-0352-x