Avidity characterization of genetically engineered T-cells with novel and established approaches

BACKGROUND: Adoptive transfer of genetically engineered autologous T-cells is becoming a successful therapy for cancer. The avidity of the engineered T-cells is of crucial importance for therapy success. We have in the past cloned a T-cell receptor (TCR) that recognizes an HLA-A2 (MHC class I)-restr...

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Detalles Bibliográficos
Autores principales: Hillerdal, Victoria, Boura, Vanessa F., Björkelund, Hanna, Andersson, Karl, Essand, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944473/
https://www.ncbi.nlm.nih.gov/pubmed/27411667
http://dx.doi.org/10.1186/s12865-016-0162-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944473/
https://www.ncbi.nlm.nih.gov/pubmed/27411667
http://dx.doi.org/10.1186/s12865-016-0162-z

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