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Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage

BACKGROUND: Chemotherapy is one of the major treatment modalities for cancer. Metal-based compounds such as derivatives of cisplatin are in the front line of therapy against a subset of cancers, but their use is restricted by severe side-effects and the induction of resistance in treated tumors. Sub...

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Detalles Bibliográficos
Autores principales: Pesch, Theresa, Schuhwerk, Harald, Wyrsch, Philippe, Immel, Timo, Dirks, Wilhelm, Bürkle, Alexander, Huhn, Thomas, Beneke, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944496/
https://www.ncbi.nlm.nih.gov/pubmed/27412346
http://dx.doi.org/10.1186/s12885-016-2538-0