The overexpression of p16 is not a surrogate marker for high-risk human papilloma virus genotypes and predicts clinical outcomes for vulvar cancer

BACKGROUND: We aimed to evaluate the correlation between p16(ink4a)-overexpression and high risk (hr)HPV-DNA in vulvar squamous cell carcinoma (vSCC) tumors as well as the impact of both biomarkers on the prognosis of vSCC patients. METHODS: PCR-detection of (hr)HPV-DNA and immunohistochemical stain...

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Detalles Bibliográficos
Autores principales: Sznurkowski, Jacek J., Żawrocki, Anton, Biernat, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944532/
https://www.ncbi.nlm.nih.gov/pubmed/27411473
http://dx.doi.org/10.1186/s12885-016-2503-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944532/
https://www.ncbi.nlm.nih.gov/pubmed/27411473
http://dx.doi.org/10.1186/s12885-016-2503-y

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