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Dermal fibroblasts induce cell cycle arrest and block epithelial–mesenchymal transition to inhibit the early stage melanoma development

Stromal fibroblasts are an integral part of the tumor stroma and constantly interact with cancer cells to promote their initiation and progression. However, the role and function of dermal fibroblasts during the early stage of melanoma development remain poorly understood. We, therefore, designed a...

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Detalles Bibliográficos
Autores principales: Zhou, Linli, Yang, Kun, Randall Wickett, R., Zhang, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944884/
https://www.ncbi.nlm.nih.gov/pubmed/27061029
http://dx.doi.org/10.1002/cam4.707