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The real role of pseudokinase: linking diabetes to cancers

A recent paper in Nature Communications shows that pseudokinase TRIB3 has a critical role in the development of diabetes‐related cancers via interacting with SQSTM1, a selective autophagy receptor. Interrupting the TRIB3‐SQSTM1 interaction using an α‐helix peptide shows a significant antitumor effec...

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Detalles Bibliográficos
Autores principales: Li, Ke, Hu, Zhuowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944892/
https://www.ncbi.nlm.nih.gov/pubmed/27038142
http://dx.doi.org/10.1002/cam4.706