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The real role of pseudokinase: linking diabetes to cancers
A recent paper in Nature Communications shows that pseudokinase TRIB3 has a critical role in the development of diabetes‐related cancers via interacting with SQSTM1, a selective autophagy receptor. Interrupting the TRIB3‐SQSTM1 interaction using an α‐helix peptide shows a significant antitumor effec...
Autores principales: | Li, Ke, Hu, Zhuowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944892/ https://www.ncbi.nlm.nih.gov/pubmed/27038142 http://dx.doi.org/10.1002/cam4.706 |
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