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Natural Killer Cell Receptors and Cytotoxic Activity in Phosphomannomutase 2 Deficiency (PMM2-CDG)

BACKGROUND: PMM2-CDG is the most common N-glycosylation defect and shows an increased risk of recurrent and/or severe, sometimes fatal, infections in early life. We hypothesized that natural killer (NK) cells, as important mediators of the immune response against microbial pathogens and regulators o...

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Detalles Bibliográficos
Autores principales: García-López, Roberto, de la Morena-Barrio, María Eugenia, Alsina, Laia, Pérez-Dueñas, Belén, Jaeken, Jaak, Serrano, Mercedes, Casado, Mercedes, Hernández-Caselles, Trinidad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944953/
https://www.ncbi.nlm.nih.gov/pubmed/27415628
http://dx.doi.org/10.1371/journal.pone.0158863