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Pro-Oxidant Role of Silibinin in DMBA/TPA Induced Skin Cancer: (1)H NMR Metabolomic and Biochemical Study

Silibinin, a major bioactive flavonolignan in Silybum marianum, has received considerable attention in view of its anticarcinogenic activity. The present study examines its anticancer potential against 7, 12-dimethylbenz(a)anthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) induced skin...

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Detalles Bibliográficos
Autores principales: Sati, Jasmine, Mohanty, Biraja Prasad, Garg, Mohan Lal, Koul, Ashwani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944989/
https://www.ncbi.nlm.nih.gov/pubmed/27414401
http://dx.doi.org/10.1371/journal.pone.0158955