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Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability
Dengue is the most prevalent arboviral disease in humans and a major public health problem worldwide. Systemic plasma leakage, leading to hypovolemic shock and potentially fatal complications, is a critical determinant of dengue severity. Recently, we and others described a novel pathogenic effect o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944995/ https://www.ncbi.nlm.nih.gov/pubmed/27416066 http://dx.doi.org/10.1371/journal.ppat.1005738 |