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A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq

Repetitive elements (REs) comprise 40–60% of the mammalian genome and have been shown to epigenetically influence the expression of genes through the formation of fusion transcript (FTs). We previously showed that an intracisternal A particle forms an FT with the agouti gene in mice, causing obesity...

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Detalles Bibliográficos
Autores principales: Wang, Tianyuan, Santos, Janine H., Feng, Jian, Fargo, David C., Shen, Li, Riadi, Gonzalo, Keeley, Elizabeth, Rosh, Zachary S., Nestler, Eric J., Woychik, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945064/
https://www.ncbi.nlm.nih.gov/pubmed/27415830
http://dx.doi.org/10.1371/journal.pone.0159028