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A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq
Repetitive elements (REs) comprise 40–60% of the mammalian genome and have been shown to epigenetically influence the expression of genes through the formation of fusion transcript (FTs). We previously showed that an intracisternal A particle forms an FT with the agouti gene in mice, causing obesity...
Autores principales: | Wang, Tianyuan, Santos, Janine H., Feng, Jian, Fargo, David C., Shen, Li, Riadi, Gonzalo, Keeley, Elizabeth, Rosh, Zachary S., Nestler, Eric J., Woychik, Richard P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945064/ https://www.ncbi.nlm.nih.gov/pubmed/27415830 http://dx.doi.org/10.1371/journal.pone.0159028 |
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