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Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV

Arenaviruses exist worldwide and can cause hemorrhagic fever and neurologic disease. A single glycoprotein is expressed on the viral surface that mediates entry into target cells. This glycoprotein, termed GPC, contains a membrane-associated signal peptide, a receptor-binding subunit termed GP1 and...

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Detalles Bibliográficos
Autores principales: Hastie, Kathryn M., Igonet, Sébastien, Sullivan, Brian M., Legrand, Pierre, Zandonatti, Michelle A., Robinson, James E., Garry, Robert F., Rey, Félix A., Oldstone, Michael B., Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945123/
https://www.ncbi.nlm.nih.gov/pubmed/27111888
http://dx.doi.org/10.1038/nsmb.3210