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Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV
Arenaviruses exist worldwide and can cause hemorrhagic fever and neurologic disease. A single glycoprotein is expressed on the viral surface that mediates entry into target cells. This glycoprotein, termed GPC, contains a membrane-associated signal peptide, a receptor-binding subunit termed GP1 and...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945123/ https://www.ncbi.nlm.nih.gov/pubmed/27111888 http://dx.doi.org/10.1038/nsmb.3210 |