The Nature of Mutations Induced by Replication-Transcription Collisions

The DNA replication and transcription machineries share a common DNA template and thus can collide with each other co-directionally or head-on(1,2). Replication-transcription collisions can cause replication fork arrest, premature transcription termination, DNA breaks, and recombination intermediate...

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Detalles Bibliográficos
Autores principales: Sankar, T. Sabari, Wastuwidyaningtyas, Brigitta D., Dong, Yuexin, Lewis, Sarah A., Wang, Jue D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945378/
https://www.ncbi.nlm.nih.gov/pubmed/27362223
http://dx.doi.org/10.1038/nature18316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945378/
https://www.ncbi.nlm.nih.gov/pubmed/27362223
http://dx.doi.org/10.1038/nature18316

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