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Design of a hyperstable 60-subunit protein icosahedron

The icosahedron and the dodecahedron are the largest of the Platonic solids, and icosahedral protein structures are widely utilized in biological systems for packaging and transport(1,2). There has been considerable interest in repurposing such structures(3–5), for example, virus-like particles for...

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Detalles Bibliográficos
Autores principales: Hsia, Yang, Bale, Jacob B., Gonen, Shane, Shi, Dan, Sheffler, William, Fong, Kimberly K., Nattermann, Una, Xu, Chunfu, Huang, Po-Ssu, Ravichandran, Rashmi, Yi, Sue, Davis, Trisha N., Gonen, Tamir, King, Neil P., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945409/
https://www.ncbi.nlm.nih.gov/pubmed/27309817
http://dx.doi.org/10.1038/nature18010