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Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family

Reprogramming to pluripotency after overexpression of OCT4, SOX2, KLF4, and MYC is accompanied by global genomic and epigenomic changes. Histone modification and DNA methylation states in induced pluripotent stem cells (iPSCs) have been shown to be highly similar to embryonic stem cells (ESCs). Howe...

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Detalles Bibliográficos
Autores principales: Hysolli, Eriona, Tanaka, Yoshiaki, Su, Juan, Kim, Kun-Yong, Zhong, Tianyu, Janknecht, Ralf, Zhou, Xiao-Ling, Geng, Lin, Qiu, Caihong, Pan, Xinghua, Jung, Yong-Wook, Cheng, Jijun, Lu, Jun, Zhong, Mei, Weissman, Sherman M., Park, In-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945581/
https://www.ncbi.nlm.nih.gov/pubmed/27373925
http://dx.doi.org/10.1016/j.stemcr.2016.05.014