Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis

Conditional knockout mice are commonly used to study the function of specific genes in hematopoiesis. Different promoters that drive Cre expression have been utilized, with the interferon-inducible Mx1-Cre still being the most commonly used “deleter strain” in experimental hematology. However, diffe...

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Detalles Bibliográficos
Autores principales: Velasco-Hernandez, Talia, Säwén, Petter, Bryder, David, Cammenga, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945592/
https://www.ncbi.nlm.nih.gov/pubmed/27373927
http://dx.doi.org/10.1016/j.stemcr.2016.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945592/
https://www.ncbi.nlm.nih.gov/pubmed/27373927
http://dx.doi.org/10.1016/j.stemcr.2016.06.002

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