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Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer

Thrombospondin 1 is a glycoprotein that regulates cellular phenotype through interactions with its cellular receptors and extracellular matrix-binding partners. Thrombospondin 1 locally regulates angiogenesis and inflammatory responses that contribute to colorectal carcinogenesis in Apc(Min/+) mice....

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Detalles Bibliográficos
Autores principales: Soto-Pantoja, D R, Sipes, J M, Martin-Manso, G, Westwood, B, Morris, N L, Ghosh, A, Emenaker, N J, Roberts, D D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945754/
https://www.ncbi.nlm.nih.gov/pubmed/27239962
http://dx.doi.org/10.1038/oncsis.2016.37