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Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer
Thrombospondin 1 is a glycoprotein that regulates cellular phenotype through interactions with its cellular receptors and extracellular matrix-binding partners. Thrombospondin 1 locally regulates angiogenesis and inflammatory responses that contribute to colorectal carcinogenesis in Apc(Min/+) mice....
Autores principales: | Soto-Pantoja, D R, Sipes, J M, Martin-Manso, G, Westwood, B, Morris, N L, Ghosh, A, Emenaker, N J, Roberts, D D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945754/ https://www.ncbi.nlm.nih.gov/pubmed/27239962 http://dx.doi.org/10.1038/oncsis.2016.37 |
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