Cargando…

TRPA1 activation leads to neurogenic vasodilatation: involvement of reactive oxygen nitrogen species in addition to CGRP and NO

BACKGROUND AND PURPOSE: Transient receptor potential ankyrin‐1 (TRPA1) activation is known to mediate neurogenic vasodilatation. We investigated the mechanisms involved in TRPA1‐mediated peripheral vasodilatation in vivo using the TRPA1 agonist cinnamaldehyde. EXPERIMENTAL APPROACH: Changes in vascu...

Descripción completa

Detalles Bibliográficos
Autores principales: Aubdool, Aisah A, Kodji, Xenia, Abdul‐Kader, Nayaab, Heads, Richard, Fernandes, Elizabeth S, Bevan, Stuart, Brain, Susan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945766/
https://www.ncbi.nlm.nih.gov/pubmed/27189253
http://dx.doi.org/10.1111/bph.13519