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Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway

Metabolomics can be used to identify potential markers and discover new targets for future therapeutic interventions. Here, we developed a novel application of the metabonomics method based on gas chromatography-mass spectrometry (GC/MS) analysis and principal component analysis (PCA) for rapidly ex...

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Detalles Bibliográficos
Autores principales: Ma, Ting, Fan, Bo-Yi, Zhang, Chao, Zhao, Hui-Jun, Han, Chao, Gao, Cai-Yun, Luo, Jian-Guang, Kong, Ling-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945937/
https://www.ncbi.nlm.nih.gov/pubmed/27416811
http://dx.doi.org/10.1038/srep29926