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Chemo- and Stereoselective Transition-Metal-Free Amination of Amides with Azides
[Image: see text] The synthesis of α-amino carbonyl/carboxyl compounds is a contemporary challenge in organic synthesis. Herein, we present a stereoselective α-amination of amides employing simple azides that proceeds under mild conditions with release of nitrogen gas. The amide is used as the limit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945995/ https://www.ncbi.nlm.nih.gov/pubmed/27350334 http://dx.doi.org/10.1021/jacs.6b04061 |