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Self-assembly of polyphosphazene immunoadjuvant with poly(ethylene oxide) enables advanced nanoscale delivery modalities and regulated pH-dependent cellular membrane activity

Water-soluble polyphosphazene polyacids, such as poly[di(carboxylatophenoxy)phosphazene] (PCPP), have been of significant interest due to their unique immunoadjuvant and vaccine delivery properties. We report that PCPP can spontaneously self-assemble into intermolecular complexes with common formula...

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Detalles Bibliográficos
Autores principales: Andrianov, Alexander K., Marin, Alexander, Fuerst, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946082/
https://www.ncbi.nlm.nih.gov/pubmed/27441274
http://dx.doi.org/10.1016/j.heliyon.2016.e00102